Derisking the biotech frontier through expert scientific due diligence and diversification.
Our Thesis
Biology fails before we do. Over 4 million people need organ transplants annually — fewer than 5% receive one. Chronic diseases and aging drive tissue degeneration, and no integrated system exists to regenerate, replace, and maintain human health.
We are building that system. Longevity Venture Fund I targets a $250B+ market across regenerative medicine, cell therapies, organ transplantation, longevity medicine, and medical tourism.
We back founders at the earliest stages — writing conviction checks, taking board seats, and staying committed through the full company-building journey.
We started the fund with three companies that are better together and ready to add new and innovative strategies to derisk biotech investing.
We are initially raising $20 million to deploy across our founding portfolio and pipeline of breakthrough longevity opportunities.
"Regeneration when possible. Replacement when necessary. Longevity for everyone."
— LVF I Investment Committee
Focus Areas
Partial cellular reprogramming using Yamanaka factors and next-generation approaches to reverse epigenetic age, restore tissue function, and potentially extend healthspan by decades.
Capitalizing on the rapidly growing global medical tourism market by connecting patients to cutting-edge longevity treatments abroad — enabling clinical delivery of therapies not yet available domestically at scale.
Machine learning and large biological models accelerating the identification of novel longevity targets, compound screening, and clinical trial design — combined with next-generation cellular therapies engineered for precision and scale.
Pioneering the next frontier in organ transplantation — from xenotransplantation using gene-edited animal organs to 3D bioprinting of patient-specific tissues, expanding the supply of transplantable organs and reducing immune rejection.
Advancing the discovery and development of therapeutic peptides — highly targeted, bioactive molecules that modulate aging pathways, tissue repair, metabolic function, and cellular signaling with precision.
Developing autologous and allogeneic Induced Pluripotent Stem Cell (iPSC) differentiation protocols and scalable manufacturing processes to produce patient-ready cell therapies that combat chronic diseases and restore organ function.
Portfolio
Three initial investments across iPSC cell banking, xenotransplantation, and regenerative medicine clinics.
Life Beyond Limits
Personalized iPSC biobank platform converting blood samples into an immortal archive of your cellular life, enabling future regenerative therapies across 10+ disease areas.
Genetically Edited Organs for Human Transplantation
CRISPR/Cas9-based gene editing platform producing human-compatible organs from genetically modified pigs (xenotransplantation), targeting the 4M+ patients annually who need a transplant.
World-Class Regenerative Medical Centre
World-class regenerative medical centre delivering stem cell therapies, anti-aging treatments, and personalized regenerative medicine to patients globally.
3 investments made. Actively seeking more. Founders — pitch us.
Vertical Integration
Cellarion
Science & Manufacturing
Designs personalized iPSC-derived therapies. High-margin, recurring biobank revenue with 10+ cell differentiation pathways.
CrofaBiotech
Organ Replacement
Replaces failing organs with gene-edited xenotransplants. CrofaPig® reduces immune recognition by 80%.
Renue
Clinical Delivery
Delivers regenerative therapies to patients globally. World-class medical centre with active clinical operations and medical tourism programs.
Combining operational biotech expertise with disciplined private equity capital to accelerate vertical integration and deliver outsized returns in longevity.
The Team

Co-Chief Investment Officer
Seasoned PE Executive, decades as a senior executive of a publicly traded broker-dealer/investment manager with $130B+ in AUM. Recognized thought leader in biotech, strategic finance, operations, and market expansion with extensive public and private board experience. Founder of RENUE, a leading private clinic specializing in Medical Tourism and Stem Cell therapies.

Co-Chief Investment Officer
Founder of pioneering personalized medicine and regenerative therapy companies. CEO of Cellarion, with expertise in cellular therapy development, diagnostics, and commercializing innovative biotech solutions. Key driver in advancing iPSC-based therapies and translational execution across multiple medical device and biotech ventures.
Scientific Advisory Board
Pedro Gutiérrez-Castrellón, MD, PhD, MBA
Chief Medical Officer, Cellarion · CEO, Elemental Translational Research
Jonathan Lakey, PhD, MSM
Chief Science Officer, Cellarion · Professor Emeritus, UC Irvine
Zijiang (Jay) Yang, PhD
Founder & CEO, BetaCure · Harvard Medical School / MIT
Prof. Paul de Vos
Full Prof. Immunoendocrinology · Biocompatibility & Pancreatic Islets
Krista Casazza, PhD, RD, CSSD
Nutritional Biochemistry · Metabolic & Neurodegenerative Disease
Adrian Angel Mutto, PhD
CLO Biotech · National University of San Martín
Dr. Adrián Abalovich
CSO, CrofaBiotech · Xenotransplantation Pioneer · INCUCAI Regulatory Committee
Muhammad M. Mohiudin, MD, DSc
Cardiac Xenotransplantation, Univ. of Maryland · Nature Top 10 (2022)
Daniel de Florian, PhD
CIAI Argentina · UNSAM · CERN Theory Division
Marcelo Grabois
ITERA · Intellectual Property & Competitive Intelligence
Dr. Carolina Bluguermann
CONICET Assistant Researcher · National University of General San Martín (UNSAM) · Cell Technology & Stem Cells
Scientific advisors drawn from Cellarion, CrofaBiotech, and Renue portfolio companies.
Latest breakthroughs from our portfolio and the broader longevity ecosystem.
Get In Touch
Whether you're a founder building at the longevity frontier or an investor interested in the fund — we want to hear from you.
Scottsdale, Arizona